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-Structure paper
Title | Crystal structures of human 17 beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP+reveal the mechanism of substrate inhibition. |
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Journal, issue, pages | Febs J., Vol. 286, Page 2155-2166, Year 2019 |
Publish date | Oct 1, 2018 (structure data deposition date) |
Authors | Li, T. / Stephen, P. / Zhu, D.W. / Shi, R. / Lin, S.X. |
External links | Febs J. / PubMed:30768851 |
Methods | X-ray diffraction |
Resolution | 1.86 - 2.4 Å |
Structure data | PDB-6mnc: PDB-6mne: |
Chemicals | ChemComp-PEG: ChemComp-J3Z: ChemComp-HOH: ChemComp-NAP: ChemComp-GOL: |
Source |
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Keywords | OXIDOREDUCTASE / 17BETA-HSD1 / ESTRONE / FUNCTIONAL ANALYSES |