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TitleThe structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin.
Journal, issue, pagesCell. Mol. Life Sci., Vol. 76, Page 2003-2013, Year 2019
Publish dateMay 26, 2017 (structure data deposition date)
AuthorsKotal, J. / Stergiou, N. / Busa, M. / Chlastakova, A. / Berankova, Z. / Rezacova, P. / Langhansova, H. / Schwarz, A. / Calvo, E. / Kopecky, J. ...Kotal, J. / Stergiou, N. / Busa, M. / Chlastakova, A. / Berankova, Z. / Rezacova, P. / Langhansova, H. / Schwarz, A. / Calvo, E. / Kopecky, J. / Mares, M. / Schmitt, E. / Chmelar, J. / Kotsyfakis, M.
External linksCell. Mol. Life Sci. / PubMed:30747251
MethodsX-ray diffraction
Resolution1.76 Å
Structure data

PDB-5o46:
Crystal structure of Iristatin, a secreted salivary cystatin from the hard tick Ixodes ricinus
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • ixodes ricinus (castor bean tick)
Keywordshydrolase inhibitor / cystatin / protease inhibitor / tick / saliva

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