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TitleDiscovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.
Journal, issue, pagesSci Rep, Vol. 9, Page 1605-1605, Year 2019
Publish dateNov 21, 2018 (structure data deposition date)
AuthorsVousden, K.A. / Lundqvist, T. / Popovic, B. / Naiman, B. / Carruthers, A.M. / Newton, P. / Johnson, D.J.D. / Pomowski, A. / Wilkinson, T. / Dufner, P. ...Vousden, K.A. / Lundqvist, T. / Popovic, B. / Naiman, B. / Carruthers, A.M. / Newton, P. / Johnson, D.J.D. / Pomowski, A. / Wilkinson, T. / Dufner, P. / de Mendez, I. / Mallinder, P.R. / Murray, C. / Strain, M. / Connor, J. / Murray, L.A. / Sleeman, M.A. / Lowe, D.C. / Huntington, J.A. / Vaughan, T.J.
External linksSci Rep / PubMed:30733557
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-6i8s:
Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsBLOOD CLOTTING / SERPIN / PLASMINOGEN ACTIVATOR INHIBITOR-1 / PAI-1 / ANTIBODY / FAB

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