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Structure paper

TitleMANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP.
Journal, issue, pagesNat Commun, Vol. 10, Page 541-541, Year 2019
Publish dateAug 6, 2018 (structure data deposition date)
AuthorsYan, Y. / Rato, C. / Rohland, L. / Preissler, S. / Ron, D.
External linksNat Commun / PubMed:30710085
MethodsX-ray diffraction
Resolution1.57 - 2.49 Å
Structure data

PDB-6h9u:
Crystal structure of the BiP NBD and MANF SAP complex
Method: X-RAY DIFFRACTION / Resolution: 1.57 Å

PDB-6ha7:
Crystal structure of the BiP NBD and MANF complex
Method: X-RAY DIFFRACTION / Resolution: 2.49 Å

PDB-6hab:
Crystal structure of BiP V461F (apo)
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

Chemicals

ChemComp-MLT:
D-MALATE

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • cricetulus griseus (Chinese hamster)
  • mus musculus (house mouse)
KeywordsCHAPERONE / MANF / BiP / NDI / HSP70 / ARMET / NBD / GRP78

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