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Structure paper

TitleA conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
Journal, issue, pagesGenes Dev., Vol. 33, Page 236-252, Year 2019
Publish dateSep 17, 2018 (structure data deposition date)
AuthorsKeskeny, C. / Raisch, T. / Sgromo, A. / Igreja, C. / Bhandari, D. / Weichenrieder, O. / Izaurralde, E.
External linksGenes Dev. / PubMed:30692204
MethodsX-ray diffraction
Resolution2.1 - 2.2 Å
Structure data

PDB-6hom:
Drosophila NOT4 CBM peptide bound to human CAF40
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6hon:
Drosophila NOT4 CBM peptide bound to human CAF40
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
  • drosophila melanogaster (fruit fly)
KeywordsGENE REGULATION / DEADENYLATION / MRNA DECAY / CCR4-NOT / HYDROLASE / TRANSCRIPTION / UBIQUITINATION

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