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TitleDeimmunizing substitutions in Pseudomonasexotoxin domain III perturb antigen processing without eliminating T-cell epitopes.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 4667-4681, Year 2019
Publish dateAug 9, 2018 (structure data deposition date)
AuthorsMoss, D.L. / Park, H.W. / Mettu, R.R. / Landry, S.J.
External linksJ. Biol. Chem. / PubMed:30683694
MethodsX-ray diffraction
Resolution1.47 Å
Structure data

PDB-6edg:
Pseudomonas exotoxin A domain III T18H477L
Method: X-RAY DIFFRACTION / Resolution: 1.47 Å

Chemicals

ChemComp-P34:
N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE

ChemComp-HOH:
WATER

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsTRANSFERASE

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