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Structure paper

TitleA back-door Phenylalanine coordinates the stepwise hexameric loading of acyl carrier protein by the fatty acid biosynthesis enzyme beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ).
Journal, issue, pagesInt. J. Biol. Macromol., Vol. 128, Page 5-11, Year 2019
Publish dateSep 29, 2018 (structure data deposition date)
AuthorsShen, S.Q. / Hang, X.D. / Zhuang, J.J. / Zhang, L. / Bi, H.K.
External linksInt. J. Biol. Macromol. / PubMed:30677439
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-6ihc:
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) Y100A mutant in complex with holo-ACP from Helicobacter pylori
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-PN7:
N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-(2-sulfanylethyl)-beta-alaninamide

ChemComp-HOH:
WATER

Source
  • helicobacter pylori (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / Dehydrotase / fatty acid biosynthesis

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