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TitleCrystallographic Snapshots of the Zika Virus NS3 Helicase Help Visualize the Reactant Water Replenishment.
Journal, issue, pagesACS Infect Dis, Vol. 5, Page 177-183, Year 2019
Publish dateAug 2, 2018 (structure data deposition date)
AuthorsFang, J. / Jing, X. / Lu, G. / Xu, Y. / Gong, P.
External linksACS Infect Dis / PubMed:30672289
MethodsX-ray diffraction
Resolution1.752 - 2.2 Å
Structure data

PDB-6adw:
Crystal structure of the Zika virus NS3 helicase (apo form)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6adx:
Crystal structure of the Zika virus NS3 helicase (ADP-Mn2+ complex, form 1)
Method: X-RAY DIFFRACTION / Resolution: 1.752 Å

PDB-6ady:
Crystal structure of the Zika virus NS3 helicase (ADP-Mn2+ complex, form 2)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-MN:
Unknown entry

Source
  • zika virus (strain mr 766)
KeywordsHYDROLASE / Zika virus NS3 helicase / apo form / ADP-Mn2+ complex

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