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TitlePotent, multi-target serine protease inhibition achieved by a simplified beta-sheet motif.
Journal, issue, pagesPLoS ONE, Vol. 14, Page e0210842-e0210842, Year 2019
Publish dateDec 13, 2017 (structure data deposition date)
AuthorsChen, X. / Riley, B.T. / de Veer, S.J. / Hoke, D.E. / Van Haeften, J. / Leahy, D. / Swedberg, J.E. / Brattsand, M. / Hartfield, P.J. / Buckle, A.M. / Harris, J.M.
External linksPLoS ONE / PubMed:30668585
MethodsX-ray diffraction
Resolution1.927 Å
Structure data

PDB-6bvh:
Trypsin complexed with a modified sunflower trypsin inhibitor, SFTI-TCTR(N12,N14)
Method: X-RAY DIFFRACTION / Resolution: 1.927 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
  • helianthus annuus (common sunflower)
KeywordsHYDROLASE/INHIBITOR / Protease inhibitor complex / sunflower trypsin inhibitor / sfti / HYDROLASE / HYDROLASE-INHIBITOR complex

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