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Structure paper

TitleStructural insights into a high fidelity variant of SpCas9.
Journal, issue, pagesCell Res., Vol. 29, Page 183-192, Year 2019
Publish dateAug 4, 2018 (structure data deposition date)
AuthorsGuo, M. / Ren, K. / Zhu, Y. / Tang, Z. / Wang, Y. / Zhang, B. / Huang, Z.
External linksCell Res. / PubMed:30664728
MethodsX-ray diffraction
Resolution2.701 - 3.004 Å
Structure data

PDB-6aeb:
Crystal structure of xCas9 in complex with sgRNA and target DNA (AAG PAM)
Method: X-RAY DIFFRACTION / Resolution: 3.004 Å

PDB-6aeg:
Crystal structure of xCas9 in complex with sgRNA and target DNA (GAT PAM)
Method: X-RAY DIFFRACTION / Resolution: 2.701 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • streptococcus pyogenes (bacteria)
KeywordsDNA BINDING PROTEIN/RNA / enzyme / DNA BINDING PROTEIN-RNA complex / DNA BINDING PROTEIN/DNA/RNA / DNA / nuclease / DNA BINDING PROTEIN-DNA-RNA complex

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