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TitleAn Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis.
Journal, issue, pagesMol. Cell, Vol. 73, Page 763-, Year 2019
Publish dateSep 5, 2017 (structure data deposition date)
AuthorsLohman, D.C. / Aydin, D. / Von Bank, H.C. / Smith, R.W. / Linke, V. / Weisenhorn, E. / McDevitt, M.T. / Hutchins, P. / Wilkerson, E.M. / Wancewicz, B. ...Lohman, D.C. / Aydin, D. / Von Bank, H.C. / Smith, R.W. / Linke, V. / Weisenhorn, E. / McDevitt, M.T. / Hutchins, P. / Wilkerson, E.M. / Wancewicz, B. / Russell, J. / Stefely, M.S. / Beebe, E.T. / Jochem, A. / Coon, J.J. / Bingman, C.A. / Dal Peraro, M. / Pagliarini, D.J.
External linksMol. Cell / PubMed:30661980
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-6awl:
Crystal structure of human Coq9
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6dew:
Structure of human COQ9 protein with bound isoprene.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-PEF:
DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE / phospholipid*YM

ChemComp-BTB:
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-64Z:
Geraniol

ChemComp-N1S:
(2Z,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol

ChemComp-FOF:
(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol

ChemComp-FOH:
(2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol

Source
  • homo sapiens (human)
KeywordsBIOSYNTHETIC PROTEIN / TetR family / Coenzyme Q biosynthesis / lipid binding / Structural Genomics / PSI-2 / Protein Structure Initiative / Mitochondrial Protein Partnership / MPP / LIPID BINDING PROTEIN / COQ Biosynthesis / isoprene binding

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