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Structure paper

TitleSelection and Characterization of Artificial Proteins Targeting the Tubulin alpha Subunit.
Journal, issue, pagesStructure, Vol. 27, Page 497-506.e4, Year 2019
Publish dateJun 22, 2018 (structure data deposition date)
AuthorsCampanacci, V. / Urvoas, A. / Consolati, T. / Cantos-Fernandes, S. / Aumont-Nicaise, M. / Valerio-Lepiniec, M. / Surrey, T. / Minard, P. / Gigant, B.
External linksStructure / PubMed:30661854
MethodsX-ray diffraction
Resolution2.6 - 3.2 Å
Structure data

PDB-6gwc:
Tubulin:iE5 alphaRep complex
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-6gwd:
Tubulin:iiH5 alphaRep complex
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Source
  • synthetic construct (others)
  • ovis aries (sheep)
KeywordsCELL CYCLE / microtubule / ARTIFICIAL PROTEIN / ALPHAREP / cytoskeleton

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