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-Structure paper
Title | Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-gamma Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer. |
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Journal, issue, pages | J. Med. Chem., Vol. 62, Page 1837-1858, Year 2019 |
Publish date | Jun 28, 2018 (structure data deposition date) |
![]() | Kim, J. / Song, J. / Ji, H.D. / Yoo, E.K. / Lee, J.E. / Lee, S.B. / Oh, J.M. / Lee, S. / Hwang, J.S. / Yoon, H. ...Kim, J. / Song, J. / Ji, H.D. / Yoo, E.K. / Lee, J.E. / Lee, S.B. / Oh, J.M. / Lee, S. / Hwang, J.S. / Yoon, H. / Kim, D.S. / Lee, S.J. / Jeong, M. / Kim, K.H. / Choi, H.S. / Lee, S.W. / Park, K.G. / Lee, I.K. / Kim, S.H. / Hwang, H. / Jeon, Y.H. / Chin, J. / Cho, S.J. |
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Methods | X-ray diffraction |
Resolution | 2.9 Å |
Structure data | ![]() PDB-6a6k: |
Chemicals | ![]() ChemComp-9S6: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSCRIPTION / Sodium iodide symporter (NIS) / Anaplastic thyroid cancer / Estrogen-related receptor gamma / Radioiodine therapy |