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TitleStructural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila.
Journal, issue, pagesNucleic Acids Res., Vol. 47, Page 3142-3157, Year 2019
Publish dateMay 4, 2018 (structure data deposition date)
AuthorsLv, M. / Yao, Y. / Li, F. / Xu, L. / Yang, L. / Gong, Q. / Xu, Y.Z. / Shi, Y. / Fan, Y.J. / Tang, Y.
External linksNucleic Acids Res. / PubMed:30649456
MethodsX-ray diffraction
Resolution2.899 Å
Structure data

PDB-5ztm:
Crystal structure of MLE dsRBDs in complex with roX2 (R2H1)
Method: X-RAY DIFFRACTION / Resolution: 2.899 Å

Source
  • drosophila melanogaster (fruit fly)
KeywordsHYDROLASE/RNA / Helicase / LncRNA / HYDROLASE-RNA complex

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