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Structure paper

TitleDistinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody.
Journal, issue, pagesCell, Vol. 176, Page 479-490.e12, Year 2019
Publish dateJun 8, 2018 (structure data deposition date)
AuthorsWingler, L.M. / McMahon, C. / Staus, D.P. / Lefkowitz, R.J. / Kruse, A.C.
External linksCell / PubMed:30639100
MethodsX-ray diffraction
Resolution2.901 Å
Structure data

PDB-6do1:
Structure of nanobody-stabilized angiotensin II type 1 receptor bound to S1I8
Method: X-RAY DIFFRACTION / Resolution: 2.901 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CL:
Unknown entry

ChemComp-OLC:
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • escherichia coli (E. coli)
  • synthetic construct (others)
KeywordsMEMBRANE PROTEIN / nanobody / GPCR / synthetic antibody

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