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Structure paper

TitleInward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1.
Journal, issue, pagesNat Commun, Vol. 10, Page 88-88, Year 2019
Publish dateJun 28, 2018 (structure data deposition date)
AuthorsKodan, A. / Yamaguchi, T. / Nakatsu, T. / Matsuoka, K. / Kimura, Y. / Ueda, K. / Kato, H.
External linksNat Commun / PubMed:30622258
MethodsX-ray diffraction
Resolution1.9 - 3.02 Å
Structure data

PDB-6a6m:
Crystal structure of an outward-open nucleotide-bound state of the eukaryotic ABC multidrug transporter CmABCB1
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-6a6n:
Crystal structure of an inward-open apo state of the eukaryotic ABC multidrug transporter CmABCB1
Method: X-RAY DIFFRACTION / Resolution: 3.02 Å

Chemicals

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-DMU:
DECYL-BETA-D-MALTOPYRANOSIDE / detergent*YM

ChemComp-NO3:
NITRATE ION

ChemComp-HOH:
WATER

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

Source
  • cyanidioschyzon merolae strain 10d (eukaryote)
KeywordsTRANSPORT PROTEIN / TRANSPORT PROTEIN ALPHA-HELICAL / ALPHA-HELICAL

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