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| Title | N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology. |
|---|---|
| Journal, issue, pages | Acs Chem Neurosci, Vol. 10, Page 1841-1853, Year 2019 |
| Publish date | Mar 14, 2018 (structure data deposition date) |
Authors | Pallesen, J. / Mollerud, S. / Frydenvang, K. / Pickering, D.S. / Bornholdt, J. / Nielsen, B. / Pasini, D. / Han, L. / Marconi, L. / Kastrup, J.S. / Johansen, T.N. |
External links | Acs Chem Neurosci / PubMed:30620174 |
| Methods | X-ray diffraction |
| Resolution | 1.85 Å |
| Structure data | ![]() PDB-6fz4: |
| Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-EC8: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
| Source |
|
Keywords | MEMBRANE PROTEIN / Kainate receptor ligand-binding domain / GluK1-S1S2 |
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