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Structure paper

TitleDrug Design Inspired by Nature: Crystallographic Detection of an Auto-Tailored Protease Inhibitor Template.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 58, Page 4051-4055, Year 2019
Publish dateOct 10, 2018 (structure data deposition date)
AuthorsGall, F.M. / Hohl, D. / Frasson, D. / Wermelinger, T. / Mittl, P.R.E. / Sievers, M. / Riedl, R.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:30615822
MethodsX-ray diffraction
Resolution1.709 Å
Structure data

PDB-6hv2:
MMP-13 in complex with the peptide IMISF
Method: X-RAY DIFFRACTION / Resolution: 1.709 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsMETAL BINDING PROTEIN / peptidase / matrix metallo protease / self-degradation / MMP

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