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TitleNovel Fluorescence Competition Assay for Retinoic Acid Binding Proteins.
Journal, issue, pagesACS Med Chem Lett, Vol. 9, Page 1297-1300, Year 2018
Publish dateSep 7, 2018 (structure data deposition date)
AuthorsTomlinson, C.W.E. / Chisholm, D.R. / Valentine, R. / Whiting, A. / Pohl, E.
External linksACS Med Chem Lett / PubMed:30613343
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-6hkr:
Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC271.
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-G9Q:
4-[2-(4,4-dimethyl-1-propan-2-yl-2,3-dihydroquinolin-6-yl)ethynyl]benzoic acid

ChemComp-GOL:
GLYCEROL

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Retinoid / Fluorescent / DC271 / CRABPII

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