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-Structure paper
Title | Covalent inhibition of histone deacetylase 8 by 3,4-dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine. |
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Journal, issue, pages | Biochim Biophys Acta Gen Subj, Vol. 1863, Page 577-585, Year 2019 |
Publish date | May 16, 2018 (structure data deposition date) |
Authors | Muth, M. / Jansch, N. / Kopranovic, A. / Kramer, A. / Wossner, N. / Jung, M. / Kirschhofer, F. / Meyer-Almes, F.J. |
External links | Biochim Biophys Acta Gen Subj / PubMed:30611847 |
Methods | X-ray diffraction |
Resolution | 1.47 Å |
Structure data | PDB-6gjk: |
Chemicals | ChemComp-ZN: ChemComp-K: ChemComp-1PE: ChemComp-PEG: ChemComp-F0Z: ChemComp-ACT: ChemComp-MLT: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / HDAH / HDAC / P2742 / PD 404182 / HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE / HISTONE DEACETYLASE / covalent modification |