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Structure paper

TitleA crystal structure of the human protein kinase Mps1 reveals an ordered conformation of the activation loop.
Journal, issue, pagesProteins, Vol. 87, Page 348-352, Year 2019
Publish dateJun 21, 2018 (structure data deposition date)
AuthorsRoorda, J.C. / Joosten, R.P. / Perrakis, A. / Hiruma, Y.
External linksProteins / PubMed:30582207
MethodsX-ray diffraction
Resolution2.41 Å
Structure data

PDB-6gvj:
Human Mps1 kinase domain with ordered activation loop
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / MPS1 / TTK / KINASE / MITOSIS CHECKPOINT / Activation loop / activation segment

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