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-Structure paper
Title | The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release. |
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Journal, issue, pages | Commun Biol, Vol. 1, Page 226-226, Year 2018 |
Publish date | Mar 14, 2018 (structure data deposition date) |
Authors | Cao, H. / Gao, M. / Zhou, H. / Skolnick, J. |
External links | Commun Biol / PubMed:30564747 |
Methods | X-ray diffraction |
Resolution | 1.03 - 2.2 Å |
Structure data | PDB-6cqa: PDB-6cw7: PDB-6cxk: PDB-6cyv: |
Chemicals | ChemComp-SO4: ChemComp-PQD: ChemComp-HOH: ChemComp-THG: ChemComp-CL: ChemComp-MG: ChemComp-DHF: ChemComp-NAP: |
Source |
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Keywords | OXIDOREDUCTASE / DHFR / dihydrofolate reductase / inhibitor / complex / tetrahydrofolate / dihydrofolate / NADP / ternary complex |