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Title | A Triazolotriazine-Based Dual GSK-3 beta /CK-1 delta Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition. |
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Journal, issue, pages | Chemmedchem, Vol. 14, Page 310-314, Year 2019 |
Publish date | Jul 10, 2018 (structure data deposition date) |
![]() | Redenti, S. / Marcovich, I. / De Vita, T. / Perez, C. / De Zorzi, R. / Demitri, N. / Perez, D.I. / Bottegoni, G. / Bisignano, P. / Bissaro, M. ...Redenti, S. / Marcovich, I. / De Vita, T. / Perez, C. / De Zorzi, R. / Demitri, N. / Perez, D.I. / Bottegoni, G. / Bisignano, P. / Bissaro, M. / Moro, S. / Martinez, A. / Storici, P. / Spalluto, G. / Cavalli, A. / Federico, S. |
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Methods | X-ray diffraction |
Resolution | 2.3 Å |
Structure data | ![]() PDB-6h0u: |
Chemicals | ![]() ChemComp-FKB: ![]() ChemComp-MLI: ![]() ChemComp-GOL: ![]() ChemComp-CL: ![]() ChemComp-NA: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Protein Kinase / GSK3beta-Covalent Inhibitor Complex / Parkinson Disease |