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Structure paper

TitleCrystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 1831-1845, Year 2019
Publish dateSep 25, 2018 (structure data deposition date)
AuthorsBitra, A. / Doukov, T. / Destito, G. / Croft, M. / Zajonc, D.M.
External linksJ. Biol. Chem. / PubMed:30545939
MethodsX-ray diffraction
Resolution2.5 - 2.65 Å
Structure data

PDB-6mkb:
Crystal structure of murine 4-1BB ligand
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-6mkz:
Crystal structure of murine 4-1BB/4-1BBL complex
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / TNF / dimer / TNFR

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