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-Structure paper
Title | 1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation. |
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Journal, issue, pages | J. Med. Chem., Vol. 62, Page 1902-1916, Year 2019 |
Publish date | Aug 3, 2018 (structure data deposition date) |
Authors | Naret, T. / Khelifi, I. / Provot, O. / Bignon, J. / Levaique, H. / Dubois, J. / Souce, M. / Kasselouri, A. / Deroussent, A. / Paci, A. ...Naret, T. / Khelifi, I. / Provot, O. / Bignon, J. / Levaique, H. / Dubois, J. / Souce, M. / Kasselouri, A. / Deroussent, A. / Paci, A. / Varela, P.F. / Gigant, B. / Alami, M. / Hamze, A. |
External links | J. Med. Chem. / PubMed:30525602 |
Methods | X-ray diffraction |
Resolution | 2.75 Å |
Structure data | PDB-6h9b: |
Chemicals | ChemComp-SO4: ChemComp-GTP: ChemComp-MG: ChemComp-GDP: ChemComp-FWH: ChemComp-HOH: |
Source |
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Keywords | TRANSPORT PROTEIN / cytoskeleton / cell division / intracellular transport |