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Structure paper

TitleStructural basis for neutralization of cytotoxic abrin by monoclonal antibody D6F10.
Journal, issue, pagesFEBS J., Vol. 286, Page 1003-1029, Year 2019
Publish dateJan 5, 2018 (structure data deposition date)
AuthorsBansia, H. / Bagaria, S. / Karande, A.A. / Ramakumar, S.
External linksFEBS J. / PubMed:30521151
MethodsX-ray diffraction
Resolution1.3 - 1.7 Å
Structure data

PDB-5z37:
Crystal Structure of Abrin A chain (Recombinant) at 1.3 Angstroms
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-5z3i:
Crystal Structure of Abrin A chain (Recombinant) in complex with Adenine at 1.65 Angstroms
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-5z3j:
Crystal Structure of Abrin A chain (Recombinant) in complex with Nicotinamide at 1.7 Angstroms
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-IMD:
IMIDAZOLE

ChemComp-HOH:
WATER

ChemComp-ADE:
ADENINE

ChemComp-NCA:
NICOTINAMIDE / medication*YM

Source
  • abrus precatorius (Indian licorice)
KeywordsHYDROLASE / Ribosome Inactivating Protein

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