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TitleTargeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Journal, issue, pagesNat Commun, Vol. 9, Page 5200-5200, Year 2018
Publish dateOct 2, 2018 (structure data deposition date)
AuthorsLiu, J. / Duan, Z. / Guo, W. / Zeng, L. / Wu, Y. / Chen, Y. / Tai, F. / Wang, Y. / Lin, Y. / Zhang, Q. ...Liu, J. / Duan, Z. / Guo, W. / Zeng, L. / Wu, Y. / Chen, Y. / Tai, F. / Wang, Y. / Lin, Y. / Zhang, Q. / He, Y. / Deng, J. / Stewart, R.L. / Wang, C. / Lin, P.C. / Ghaffari, S. / Evers, B.M. / Liu, S. / Zhou, M.M. / Zhou, B.P. / Shi, J.
External linksNat Commun / PubMed:30518851
MethodsNMR (solution)
Structure data

PDB-6mnl:
NMR solution structures of second bromodomain of BRD4 with FOXO3a peptide
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / BRD4 / CDK6 / AKT / luminal breast cancer

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