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TitleAn ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb.
Journal, issue, pagesNucleic Acids Res., Vol. 47, Page 1523-1531, Year 2019
Publish dateApr 13, 2018 (structure data deposition date)
AuthorsShortridge, M.D. / Wille, P.T. / Jones, A.N. / Davidson, A. / Bogdanovic, J. / Arts, E. / Karn, J. / Robinson, J.A. / Varani, G.
External linksNucleic Acids Res. / PubMed:30481318
MethodsNMR (solution)
Structure data

PDB-6d2u:
Solution structure of a ultra-high affinity macrocycle bound to HIV-1 TAR RNA
Method: SOLUTION NMR

Source
  • synthetic construct (others)
KeywordsPeptide/RNA / Macrocycle inhibitor / complex / HIV-1 TAR / Tat / P-TEFb / RNA / Peptide-RNA complex

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