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Structure paper

TitleDirect interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.
Journal, issue, pagesNucleic Acids Res., Vol. 47, Page 1225-1238, Year 2019
Publish dateDec 14, 2017 (structure data deposition date)
AuthorsIvanochko, D. / Halabelian, L. / Henderson, E. / Savitsky, P. / Jain, H. / Marcon, E. / Duan, S. / Hutchinson, A. / Seitova, A. / Barsyte-Lovejoy, D. ...Ivanochko, D. / Halabelian, L. / Henderson, E. / Savitsky, P. / Jain, H. / Marcon, E. / Duan, S. / Hutchinson, A. / Seitova, A. / Barsyte-Lovejoy, D. / Filippakopoulos, P. / Greenblatt, J. / Lima-Fernandes, E. / Arrowsmith, C.H.
External linksNucleic Acids Res. / PubMed:30462309
MethodsX-ray diffraction
Resolution2 - 2.2 Å
Structure data

PDB-6bw3:
Crystal structure of RBBP4 in complex with PRDM3 N-terminal peptide
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6bw4:
Crystal structure of RBBP4 in complex with PRDM16 N-terminal peptide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / NuRD / Complex / Epigenetics / Structural Genomics / Structural Genomics Consortium / SGC / Histone-binding protein / Chromatin regulator / Nucleus / Repressor / WD repeat

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