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-Structure paper
Title | A structural mechanism for directing corepressor-selective inverse agonism of PPAR gamma. |
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Journal, issue, pages | Nat Commun, Vol. 9, Page 4687-4687, Year 2018 |
Publish date | Jan 4, 2018 (structure data deposition date) |
Authors | Brust, R. / Shang, J. / Fuhrmann, J. / Mosure, S.A. / Bass, J. / Cano, A. / Heidari, Z. / Chrisman, I.M. / Nemetchek, M.D. / Blayo, A.L. ...Brust, R. / Shang, J. / Fuhrmann, J. / Mosure, S.A. / Bass, J. / Cano, A. / Heidari, Z. / Chrisman, I.M. / Nemetchek, M.D. / Blayo, A.L. / Griffin, P.R. / Kamenecka, T.M. / Hughes, T.S. / Kojetin, D.J. |
External links | Nat Commun / PubMed:30409975 |
Methods | X-ray diffraction |
Resolution | 2.26 Å |
Structure data | PDB-6c1i: |
Chemicals | ChemComp-EEY: ChemComp-KNA: ChemComp-HOH: |
Source |
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Keywords | TRANSCRIPTION / Nuclear receptors / TZDs / Drug design / Therapeutic targets |