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TitleBlocking the proteolytic activity of zymogen matriptase with antibody-based inhibitors.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 314-326, Year 2019
Publish dateSep 28, 2016 (structure data deposition date)
AuthorsTamberg, T. / Hong, Z. / De Schepper, D. / Skovbjerg, S. / Dupont, D.M. / Vitved, L. / Schar, C.R. / Skjoedt, K. / Vogel, L.K. / Jensen, J.K.
External linksJ. Biol. Chem. / PubMed:30409910
MethodsX-ray diffraction
Resolution2.498 Å
Structure data

PDB-5lyo:
Crystal structure of the zymogen matriptase catalytic domain
Method: X-RAY DIFFRACTION / Resolution: 2.498 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHydrolase/Inhibitor / Serine protease / enzyme inhibitor / zymogen / Hydrolase-Inhibitor complex

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