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TitleA Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Journal, issue, pagesCell Rep, Vol. 25, Page 1385-1394.e7, Year 2018
Publish dateMay 14, 2018 (structure data deposition date)
AuthorsKeeffe, J.R. / Van Rompay, K.K.A. / Olsen, P.C. / Wang, Q. / Gazumyan, A. / Azzopardi, S.A. / Schaefer-Babajew, D. / Lee, Y.E. / Stuart, J.B. / Singapuri, A. ...Keeffe, J.R. / Van Rompay, K.K.A. / Olsen, P.C. / Wang, Q. / Gazumyan, A. / Azzopardi, S.A. / Schaefer-Babajew, D. / Lee, Y.E. / Stuart, J.B. / Singapuri, A. / Watanabe, J. / Usachenko, J. / Ardeshir, A. / Saeed, M. / Agudelo, M. / Eisenreich, T. / Bournazos, S. / Oliveira, T.Y. / Rice, C.M. / Coffey, L.L. / MacDonald, M.R. / Bjorkman, P.J. / Nussenzweig, M.C. / Robbiani, D.F.
External linksCell Rep / PubMed:30403995
MethodsX-ray diffraction
Resolution2.07 - 2.48 Å
Structure data

PDB-6dfi:
Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII
Method: X-RAY DIFFRACTION / Resolution: 2.48 Å

PDB-6dfj:
Crystal structure of anti-Zika antibody Z021 bound to DENV-1 envelope protein DIII
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • zika virus
  • dengue virus 1
KeywordsIMMUNE SYSTEM / antibody / Fab / Zika / Dengue / recurrent / neutralizing

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