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Structure paper

TitleDifferential active site requirements for NDM-1 beta-lactamase hydrolysis of carbapenem versus penicillin and cephalosporin antibiotics.
Journal, issue, pagesNat Commun, Vol. 9, Page 4524-4524, Year 2018
Publish dateJan 24, 2018 (structure data deposition date)
AuthorsSun, Z. / Hu, L. / Sankaran, B. / Prasad, B.V.V. / Palzkill, T.
External linksNat Commun / PubMed:30375382
MethodsX-ray diffraction
Resolution1.75006148726 Å
Structure data

PDB-6c89:
NDM-1 Beta-Lactamase Exhibits Differential Active Site Sequence Requirements for the Hydrolysis of Penicillin versus Carbapenem Antibiotics
Method: X-RAY DIFFRACTION / Resolution: 1.75006148726 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsANTIMICROBIAL PROTEIN / NDM-1; beta-lactamase; deep sequencing; antibiotic resistance; beta-lactams

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