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TitleStructural basis of latent TGF-beta 1 presentation and activation by GARP on human regulatory T cells.
Journal, issue, pagesScience, Vol. 362, Page 952-956, Year 2018
Publish dateApr 30, 2018 (structure data deposition date)
AuthorsLienart, S. / Merceron, R. / Vanderaa, C. / Lambert, F. / Colau, D. / Stockis, J. / van der Woning, B. / De Haard, H. / Saunders, M. / Coulie, P.G. ...Lienart, S. / Merceron, R. / Vanderaa, C. / Lambert, F. / Colau, D. / Stockis, J. / van der Woning, B. / De Haard, H. / Saunders, M. / Coulie, P.G. / Savvides, S.N. / Lucas, S.
External linksScience / PubMed:30361387
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-6gff:
Structure of GARP (LRRC32) in complex with latent TGF-beta1 and MHG-8 Fab
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / GARP / TGF-B1 / Activation / Treg

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