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Structure paper

TitleStructural insights into the duplex DNA processing of TREX2
Journal, issue, pagesNucleic Acids Res., Vol. 46, Page 12166-12176, Year 2018
Publish dateJun 19, 2018 (structure data deposition date)
AuthorsCheng, H.L. / Lin, C.T. / Huang, K.W. / Wang, S. / Lin, Y.T. / Toh, S.I. / Hsiao, Y.Y.
External linksNucleic Acids Res. / PubMed:30357414
MethodsX-ray diffraction
Resolution1.9 - 2.7 Å
Structure data

PDB-6a45:
Structure of mouse TREX2
Method: X-RAY DIFFRACTION / Resolution: 1.904 Å

PDB-6a46:
Structure of TREX2 in complex with a nucleotide (dCMP)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6a47:
Structure of TREX2 in complex with a Y structured dsDNA
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-6a4b:
Structure of TREX2 in complex with a duplex DNA with 2 nucleotide 3'-overhang
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-DCM:
2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE

ChemComp-CA:
Unknown entry

ChemComp-NA:
Unknown entry

Source
  • mus musculus (house mouse)
KeywordsDNA BINDING PROTEIN / Exonuclease / DEDDh exonuclease

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