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TitleA therapeutic approach to pantothenate kinase associated neurodegeneration.
Journal, issue, pagesNat Commun, Vol. 9, Page 4399-4399, Year 2018
Publish dateSep 25, 2017 (structure data deposition date)
AuthorsSharma, L.K. / Subramanian, C. / Yun, M.K. / Frank, M.W. / White, S.W. / Rock, C.O. / Lee, R.E. / Jackowski, S.
External linksNat Commun / PubMed:30352999
MethodsX-ray diffraction
Resolution1.601 Å
Structure data

PDB-6b3v:
PANK3 complex with compound PZ-2891
Method: X-RAY DIFFRACTION / Resolution: 1.601 Å

Chemicals

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-7DQ:
6-(4-{[4-(propan-2-yl)phenyl]acetyl}piperazin-1-yl)pyridazine-3-carbonitrile

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/INHIBITOR / PANK / Inhibitor / Complex / Transferase / Pantothenate kinase / TRANSFERASE-INHIBITOR complex

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