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TitleFamotidine, an Antiulcer Agent, Strongly InhibitsHelicobacter pyloriand Human Carbonic Anhydrases.
Journal, issue, pagesACS Med Chem Lett, Vol. 9, Page 1035-1038, Year 2018
Publish dateMar 26, 2018 (structure data deposition date)
AuthorsAngeli, A. / Ferraroni, M. / Supuran, C.T.
External linksACS Med Chem Lett / PubMed:30344913
MethodsX-ray diffraction
Resolution1.01 - 1.69 Å
Structure data

PDB-6g3q:
Crystal structure of human carbonic anhydrase II in complex with the inhibitor famotidine
Method: X-RAY DIFFRACTION / Resolution: 1.01 Å

PDB-6g3v:
Crystal structure of human carbonic anhydrase I in complex with the inhibitor famotidine
Method: X-RAY DIFFRACTION / Resolution: 1.69 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-FO9:
famotidine / medication, antagonist*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE

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