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TitleStructural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin-antitoxin system: targeting a tRNase to tackle mycobacterial adaptation.
Journal, issue, pagesNucleic Acids Res., Vol. 46, Page 11639-11655, Year 2018
Publish dateJul 4, 2018 (structure data deposition date)
AuthorsDeep, A. / Tiwari, P. / Agarwal, S. / Kaundal, S. / Kidwai, S. / Singh, R. / Thakur, K.G.
External linksNucleic Acids Res. / PubMed:30329074
MethodsX-ray diffraction
Resolution1.67 Å
Structure data

PDB-6a7v:
Crystal structure of Mycobacterium tuberculosis VapBC11 toxin-antitoxin complex
Method: X-RAY DIFFRACTION / Resolution: 1.67 Å

Chemicals

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis h37rv (bacteria)
KeywordsTOXIN/ANTITOXIN / VapBC / Endoribonuclease / tRNase / Rv1560-Rv1561 / TOXIN / TOXIN-ANTITOXIN complex

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