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Structure paper

TitleCharacterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus.
Journal, issue, pagesNat. Immunol., Vol. 19, Page 1248-1256, Year 2018
Publish dateJan 25, 2018 (structure data deposition date)
AuthorsRenner, M. / Flanagan, A. / Dejnirattisai, W. / Puttikhunt, C. / Kasinrerk, W. / Supasa, P. / Wongwiwat, W. / Chawansuntati, K. / Duangchinda, T. / Cowper, A. ...Renner, M. / Flanagan, A. / Dejnirattisai, W. / Puttikhunt, C. / Kasinrerk, W. / Supasa, P. / Wongwiwat, W. / Chawansuntati, K. / Duangchinda, T. / Cowper, A. / Midgley, C.M. / Malasit, P. / Huiskonen, J.T. / Mongkolsapaya, J. / Screaton, G.R. / Grimes, J.M.
External linksNat. Immunol. / PubMed:30323338
MethodsX-ray diffraction
Resolution2 - 2.9 Å
Structure data

PDB-6fla:
3H5 Fab bound to EDIII of DenV 2 Xtal form 1
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-6flb:
3H5 Fab bound to EDIII of DenV 2 Xtal form 2
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6flc:
2C8 Fab bound to EDIII of DenV 2
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • dengue virus 2
KeywordsVIRAL PROTEIN / Dengue virus / antibody / macromolecular complex

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