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TitleIncreasing the distance between two monomers of topoisomerase II beta under the action of antitumor agent 4 beta-sulfur-(benzimidazole) 4'-demethylepipodophyllotoxin.
Journal, issue, pagesSci Rep, Vol. 8, Page 14949-14949, Year 2018
Publish dateFeb 7, 2018 (structure data deposition date)
AuthorsSun, L.Y. / Zhu, L.W. / Tang, Y.J.
External linksSci Rep / PubMed:30297860
MethodsX-ray diffraction
Resolution2.54 Å
Structure data

PDB-5zad:
Human topoisomerase II beta in complex with DNA
Method: X-RAY DIFFRACTION / Resolution: 2.54 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN/DNA / DNA binding and cleavage / ISOMERASE-DNA complex / DNA BINDING PROTEIN-DNA complex

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