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-Structure paper
Title | Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase. |
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Journal, issue, pages | J. Med. Chem., Vol. 61, Page 9647-9665, Year 2018 |
Publish date | Jun 27, 2018 (structure data deposition date) |
![]() | Buchler, I. / Akuma, D. / Au, V. / Carr, G. / de Leon, P. / DePasquale, M. / Ernst, G. / Huang, Y. / Kimos, M. / Kolobova, A. ...Buchler, I. / Akuma, D. / Au, V. / Carr, G. / de Leon, P. / DePasquale, M. / Ernst, G. / Huang, Y. / Kimos, M. / Kolobova, A. / Poslusney, M. / Wei, H. / Swinnen, D. / Montel, F. / Moureau, F. / Jigorel, E. / Schulze, M.E.D. / Wood, M. / Barrow, J.C. |
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Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | ![]() PDB-6gy1: |
Chemicals | ![]() ChemComp-MG: ![]() ChemComp-SAH: ![]() ChemComp-FGQ: ![]() ChemComp-DMS: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Magnesium Ion Binding / O-Methyltransferase Activity / Neurotransmitter Catabolic Process |