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-Structure paper
Title | Discovery and lead identification of quinazoline-based BRD4 inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 28, Page 3483-3488, Year 2018 |
Publish date | Jul 17, 2018 (structure data deposition date) |
Authors | Yang, S.M. / Urban, D.J. / Yoshioka, M. / Strovel, J.W. / Fletcher, S. / Wang, A.Q. / Xu, X. / Shah, P. / Hu, X. / Hall, M.D. ...Yang, S.M. / Urban, D.J. / Yoshioka, M. / Strovel, J.W. / Fletcher, S. / Wang, A.Q. / Xu, X. / Shah, P. / Hu, X. / Hall, M.D. / Jadhav, A. / Maloney, D.J. |
External links | Bioorg. Med. Chem. Lett. / PubMed:30268702 |
Methods | X-ray diffraction |
Resolution | 1.26 Å |
Structure data | PDB-6e4a: |
Chemicals | ChemComp-HRY: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | PROTEIN BINDING / BRD4(BD1) |