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TitleStructural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody.
Journal, issue, pagesNat Commun, Vol. 9, Page 3822-3822, Year 2018
Publish dateJul 25, 2018 (structure data deposition date)
AuthorsLennartz, F. / Brod, F. / Dabbs, R. / Miura, K. / Mekhaiel, D. / Marini, A. / Jore, M.M. / Sogaard, M.M. / Jorgensen, T. / de Jongh, W.A. ...Lennartz, F. / Brod, F. / Dabbs, R. / Miura, K. / Mekhaiel, D. / Marini, A. / Jore, M.M. / Sogaard, M.M. / Jorgensen, T. / de Jongh, W.A. / Sauerwein, R.W. / Long, C.A. / Biswas, S. / Higgins, M.K.
External linksNat Commun / PubMed:30237518
MethodsX-ray diffraction
Resolution3.23 Å
Structure data

PDB-6h5n:
Plasmodium falciparum Pfs48/45 C-terminal domain bound to monoclonal antibody 85RF45.1
Method: X-RAY DIFFRACTION / Resolution: 3.23 Å

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • rattus norvegicus (Norway rat)
KeywordsCELL INVASION / Pfs48/45 Gamete Fusion Plasmodium falciparum Transmission blocking Monoclonal Antibody

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