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TitleDevelopment of an antibody fragment that stabilizes GPCR/G-protein complexes.
Journal, issue, pagesNat Commun, Vol. 9, Page 3712-3712, Year 2018
Publish dateMar 19, 2018 (structure data deposition date)
AuthorsMaeda, S. / Koehl, A. / Matile, H. / Hu, H. / Hilger, D. / Schertler, G.F.X. / Manglik, A. / Skiniotis, G. / Dawson, R.J.P. / Kobilka, B.K.
External linksNat Commun / PubMed:30213947
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-6crk:
Heterotrimeric G-protein in complex with an antibody fragment
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-FLC:
CITRATE ANION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / Heterotrimeric G-protein antibody fragment

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