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Structure paper

TitleStructural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.
Journal, issue, pagesMol. Cell, Vol. 71, Page 1001-1011.e4, Year 2018
Publish dateJun 19, 2018 (structure data deposition date)
AuthorsDoxtader, K.A. / Wang, P. / Scarborough, A.M. / Seo, D. / Conrad, N.K. / Nam, Y.
External linksMol. Cell / PubMed:30197297
MethodsX-ray diffraction
Resolution1.7 - 3.006 Å
Structure data

PDB-6du4:
Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 1
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-6du5:
Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 6
Method: X-RAY DIFFRACTION / Resolution: 3.006 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTransferase/RNA / RNA methylation / Methyltransferase / protein-RNA complex / m6A and n6-methyladenosine / Transferase-RNA complex / m6a methylation / Protein-RNA structure / m6a / N6-methyladenosine

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