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TitleA cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 115, Page E8900-E8908, Year 2018
Publish dateMar 8, 2017 (structure data deposition date)
AuthorsSadler, J.B.A. / Wenzel, D.M. / Williams, L.K. / Guindo-Martinez, M. / Alam, S.L. / Mercader, J.M. / Torrents, D. / Ullman, K.S. / Sundquist, W.I. / Martin-Serrano, J.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:30181294
MethodsX-ray diffraction
Resolution1.868 - 1.906 Å
Structure data

PDB-5v3r:
CHMP4C in complex with ALIX BRO1
Method: X-RAY DIFFRACTION / Resolution: 1.906 Å

PDB-5wa1:
CHMP4C A232T in complex with ALIX BRO1
Method: X-RAY DIFFRACTION / Resolution: 1.868 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL DIVISION / TRANSPORT PROTEIN / abscission checkpoint / CELL CYCLE

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