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Structure paper

TitleMolecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 504, Page 89-95, Year 2018
Publish dateAug 25, 2018 (structure data deposition date)
AuthorsYun, J.S. / Yoon, J.H. / Choi, Y.J. / Son, Y.J. / Kim, S. / Tong, L. / Chang, J.H.
External linksBiochem. Biophys. Res. Commun. / PubMed:30180947
MethodsX-ray diffraction
Resolution1.8 - 1.902 Å
Structure data

PDB-6aix:
Crystal structure of DXO in complex with adenosine 3', 5' bisphosphate and two magnesium ions
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-6aiy:
Crystal structure of DXO (E234A mutant) in complex with adenosine 3', 5' bisphosphate and two magnesium ions
Method: X-RAY DIFFRACTION / Resolution: 1.902 Å

Chemicals

ChemComp-A3P:
ADENOSINE-3'-5'-DIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / 5[prime]-3[prime] exoribonuclease / DXO / adenosine 3[ prime] and 5[prime] bisphosphate / nuclease inhibitor / HYDROLASE-HYDROLASE INHIBITOR complex / 5'to 3' exoribonuclease / adenosine 3' / 5' bisphosphate

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