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Structure paper

TitleVariable heavy-variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly.
Journal, issue, pagesProtein Eng. Des. Sel., Vol. 31, Page 289-299, Year 2018
Publish dateMay 7, 2018 (structure data deposition date)
AuthorsRegula, J.T. / Imhof-Jung, S. / Molhoj, M. / Benz, J. / Ehler, A. / Bujotzek, A. / Schaefer, W. / Klein, C.
External linksProtein Eng. Des. Sel. / PubMed:30169707
MethodsX-ray diffraction
Resolution1.88 Å
Structure data

PDB-6ghg:
Variable heavy - variable light domain and Fab-arm CrossMabs with charged residue exchanges
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-P6G:
HEXAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / ANTIBODY / FAB FRAGMENT / DP47 / ANG2 / VEGF / CROSSMAB / CHARGE VARIANTS

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