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-Structure paper
Title | Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities. |
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Journal, issue, pages | J. Med. Chem., Vol. 61, Page 7877-7891, Year 2018 |
Publish date | Apr 26, 2018 (structure data deposition date) |
Authors | Wang, Q. / Arnst, K.E. / Wang, Y. / Kumar, G. / Ma, D. / Chen, H. / Wu, Z. / Yang, J. / White, S.W. / Miller, D.D. / Li, W. |
External links | J. Med. Chem. / PubMed:30122035 |
Methods | X-ray diffraction |
Resolution | 2.853 Å |
Structure data | PDB-6d88: |
Chemicals | ChemComp-GTP: ChemComp-CA: ChemComp-MG: ChemComp-GDP: ChemComp-MES: ChemComp-G9K: ChemComp-ACP: ChemComp-HOH: |
Source |
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Keywords | CELL CYCLE / Microtubule Inhibitor / Colchicine / Cancer |