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TitleArsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells.
Journal, issue, pagesNat Commun, Vol. 9, Page 3069-3069, Year 2018
Publish dateJun 21, 2018 (structure data deposition date)
AuthorsKozono, S. / Lin, Y.M. / Seo, H.S. / Pinch, B. / Lian, X. / Qiu, C. / Herbert, M.K. / Chen, C.H. / Tan, L. / Gao, Z.J. ...Kozono, S. / Lin, Y.M. / Seo, H.S. / Pinch, B. / Lian, X. / Qiu, C. / Herbert, M.K. / Chen, C.H. / Tan, L. / Gao, Z.J. / Massefski, W. / Doctor, Z.M. / Jackson, B.P. / Chen, Y. / Dhe-Paganon, S. / Lu, K.P. / Zhou, X.Z.
External linksNat Commun / PubMed:30093655
MethodsX-ray diffraction
Resolution1.59 Å
Structure data

PDB-6dun:
Crystal Structure Analysis of PIN1
Method: X-RAY DIFFRACTION / Resolution: 1.59 Å

Chemicals

ChemComp-TAS:
TRIHYDROXYARSENITE(III)

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / prolyl isomerase

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